Developments in Parkinson’s Disease Testing Methods

The Syn-One skin test is a confirmatory diagnostic tool that physicians may use to evaluate patients for synucleinopathies, a group of neurological disorders such as Parkinson’s Disease. While the test may not predict future disease development, the phosphorylated α-synuclein (P-SYN) skin biopsy marker may aid in early diagnosis before symptoms appear, allowing for timely interventions and better outcomes, including delaying cognitive impairment.

Increasing patient awareness of new testing options is crucial for informed decision-making during the diagnostic process. Further research is needed to fully understand the role of P-SYN testing, but a recently published article provides insight into the potential future of PD biomarker testing. This test is now commercially available for clinicians and offers high sensitivity and specificity for the diagnosis of Parkinson’s Disease in patients who have confirmed α-synuclein pathology.